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电化学(中英文) ›› 2019, Vol. 25 ›› Issue (3): 291-301.  doi: 10.13208/j.electrochem.181059

• 综述 • 上一篇    下一篇

纳流控-电化学技术在生化分析领域的研究进展

李仲秋,吴增强,夏兴华*   

  1. 南京大学生命分析化学国家重点实验室,南京大学化学化工学院,江苏 南京 210023
  • 收稿日期:2019-03-12 修回日期:2019-04-24 出版日期:2019-06-25 发布日期:2019-04-24
  • 通讯作者: 夏兴华http://chem.nju.edu.cn/staff/staff.asp?iname=%CF%C4%D0%CB%BB%AA E-mail:xhxia@nju.edu.cn
  • 基金资助:
     
    国家重点研发计划项目(No. 2017YFA0700500)、国家自然科学基金项目(No. 21635004, No. 21775066)资助

Recent Advances in Nanofluidic Electrochemistry for Biochemical Analysis

LI Zhong-qiu, WU Zeng-qiang, XIA Xing-hua*   

  1. State Key Laboratory of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210023, China
  • Received:2019-03-12 Revised:2019-04-24 Published:2019-06-25 Online:2019-04-24
  • Contact: XIA Xing-hua E-mail:xhxia@nju.edu.cn

摘要:

纳流控作为一个崭新的研究领域正受到越来越多的关注,并且已被成功应用到纳米尺度分离、生化传感、能量转化等诸多领域. 纳流控的发展与电化学紧密相连,一方面,电化学可以为纳米孔道中的物质传输特性的研究提供驱动力;另一方面,纳米孔道可以为限域电化学研究提供微环境. 纳流控和电化学技术相辅相成,催生了许多单分子、单粒子分析以及纳米流体操控的新理念与新技术. 本综述从纳米孔道与电极的结合方式出发,对纳流控-电化学相关研究进行了总结与展望.

关键词: 纳流控, 电化学, 物质传输单分子分析, 氧化还原循环, 双极电极, 场效应管

Abstract:

Nanofluidics, as a young research field, has been receiving more and more attentions. It has been successfully applied in various fields including nanoscale separation, biochemical sensing and energy conversion. The development of nanofluidics is closely related to electrochemistry that can provide a driving force for the study of the material transport characteristics in nanopores/nanochannels. On the other hand, nanopores/nanochannels can creat a microenvironment for study of spatially nanoconfined electrochemistry. The combination of nanofluidics and electrochemistry has given rise to many new theories and technologies for single molecule/particle analysis and nanofluid manipulation. Herein, we provide a review of the recent progresses in nanofluidic electrochemistry based on the combination of nanopore and electrode, and finally give a brief outlook on this field.

Key words: nanofluidics, electrochemistry, mass transport, single-molecule analysis, redox cycling, bipolar electrode, field-effect transistor

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