纳米金双巯基修饰金电极差分脉冲伏安法测定多巴胺和抗坏血酸

doi:10.61558/2993-074X.1793

电化学（中英文） ›› 2007, Vol. 13 ›› Issue (2): 127-131. doi: 10.61558/2993-074X.1793

纳米金双巯基修饰金电极差分脉冲伏安法测定多巴胺和抗坏血酸

汪海燕;柳鹏;王晔;金葆康;

安徽大学化学化工学院,安徽大学化学化工学院,安徽大学化学化工学院,安徽大学化学化工学院安徽合肥230039巢湖学院化学系,安徽巢湖230038,安徽合肥230039,安徽合肥230039,安徽合肥230039

收稿日期:2007-05-28 修回日期:2007-05-28 出版日期:2007-05-28 发布日期:2007-05-28

Determination of Ddopamine and Ascorbate on Gold Nanoparticle and 4,4-bis (methanethiol) biphenyl (MTP) Self-assembled Monolayer Modified Gold Electrode

WANG Hai-yan1,2,LIU Peng1,WANG Ye1,JIN Bao-kang1

(1.School of Chemistry and Chemical Engineering,Anhui University,Hefei 230039,Anhui,China2.Department of Chemistry,chaohu College,Chaohu 230038,Anhui,China

Received:2007-05-28 Revised:2007-05-28 Published:2007-05-28 Online:2007-05-28

摘要/Abstract

摘要： 在裸金电极上自组装4,4-二甲基联苯硫醇(MTP)膜(MTP/AuSAMs),再电还原氯金酸溶液修饰纳米金,得纳米金双巯基修饰金电极(NG/MTP/Au).研究了多巴胺(DA)和抗坏血酸(AA)在NG/MTP/Au上的电化学行为,发现该修饰电极对DA、AA的氧化具有良好的电催化作用,多巴胺(DA)和抗坏血酸(AA)的氧化峰电位差达到155mV,可以实现对此二组分混合溶液的选择性测定.差分脉冲法测得的峰电流与DA、AA浓度分别在5.0×10-7～1×10-4mol.L-1和3.5×10-6～1.0×10-3mol.L-1范围内呈线性关系,检测限(3σ)分别为1.5×10-7mol.L-1和1.2×10-6mol.L-1,相关系数0.998.

关键词: 多巴胺, 抗坏血酸, 4,4-二甲基联苯硫醇, 纳米金, 差分脉冲法

Abstract: A new approach to construct an ampermetric biosensor was described.The 4,4-bis(methanethiol)biphenyl(MTP)is adsorbed on to a bare gold electrode to make self-assembled monolayers(MTP/Au SAMs).Then electrodeposited 2mg/mL HAuCl4 at-200 mV,NG/MTP/Au electrode was prepared.When a differential pulse voltammetric(DPV)technique was used,the peak separation between DA and AA is 155 mV.Hence,the selective determination of dopamine(DA)and ascorbate(AA)in the binary mixture system can be performed.Under the chosen conditions,the peak currents are correspondent linearly to the concentrations of DA and AA in the range of 5.0×10-7~1×10-4 mol·L-1 and 3.5×10-6~1.0×10-3mol·L-1,respectively.The correlation coefficients were 0.998.The detection limit were 1.5×10-7 mol·L-1 and 1.2×10-6 mol·L-1for DA and AA.

Key words: dopamine, ascorbate, gold nanpoarticle, MTP, DPV

中图分类号:

O657.1

汪海燕, 柳鹏, 王晔, 金葆康, . 纳米金双巯基修饰金电极差分脉冲伏安法测定多巴胺和抗坏血酸[J]. 电化学（中英文）, 2007, 13(2): 127-131.

WANG Hai-yan, LIU Peng, WANG Ye, JIN Bao-kang. Determination of Ddopamine and Ascorbate on Gold Nanoparticle and 4,4-bis (methanethiol) biphenyl (MTP) Self-assembled Monolayer Modified Gold Electrode[J]. Journal of Electrochemistry, 2007, 13(2): 127-131.

导出引用管理器 EndNote|Ris|BibTeX

链接本文: https://electrochem.xmu.edu.cn/CN/10.61558/2993-074X.1793

https://electrochem.xmu.edu.cn/CN/Y2007/V13/I2/127

参考文献

[1]Stamford J A,Justice J B Jr.Probing brain chemistry with electroanalytical techniques-voltammetry comes of age[J].Anal Chem,1996,68:359A-363A. [2]Boulton A,Baker G,Adams R N.Carbon electrode sur-face chemistry:optimization of bioanalytical perform-ance[M].In:Voltammetric Methods in Brain Systems,Edited by Boulton A A,Baker G B,Adams R N,To-towa:Humana Press,NJ,1995.1-26. [3]Zhang L,Jiang X.Electrochemical behavior of querce-tin:Experimental and theoretical studies[J].Electroa-nalytical Chemistry.2005,583:292299. [4]Jahan-Bakhsh Raoofr,Reza Ojani,Sahar Rashid-Nadi-mi.Voltammetric determination of ascorbic acid and do-pamine in the same sample at the surface of a carbon paste electrode modified with polypyffole/feffocyanide.[J].Electrochimica Acta,2005,50:46944698. [5]Zhao Y,Gao Y,Zhan D,et al.Selective detection of dopamine in the presence of ascorbic acid and uric acid by a carbon nanotubes-ionic[J].Talanta,2005,66:51-57. [6]Raj C R,Tokuda K,Ohsaka T.Electroanalytical appli-cations of cationic self-assembled monolayers:square-wave voltammetric determination of dopamine and ascor-bate[J].Bioelectrochemistry.2001,53:183-191. [7]Zhou Y,Hu S,Cao Z,et al.Capacitive immunosensor for the determination of Schistosoma japonicum antigen[J].Analytical Letters,2002,35:1919-1930. [8]Raj C R,Okajima T,Ohsaka T.Gold nanoparticle ar-rys for the voltammetric sensing of dopamine[J].Elec-troanalytical Chemistry.2003,543:127-133. [9]Zhang P,Wu F,Zhao G,et al.Selective response of dopamine in the presence of ascorbic acid at multi-walled carbon nanotube modified gold electrode[J].Bioelectrochemistry.2005,67:109-114. [10]Jin B,Ding S,Kametani K,et al.The preparation and electrochemical behavior of density-controlled gold nano-particle sself-assembled interface[J].Chemistry Letters,2005,34:302-303 [11]Liu S,Li X.The influence of gold nanoparticle modi-fied electrode on the structure of mercaptopropionic acid self-assembly monolayer[J].Electrochimica Ac-ta,2005,51:427-431. [12]Jia L(贾莉),Lei Q(雷秋芬),Zhang X(张修华),et al.Determination of dopamine on o-aminobenzeneth-iol self-assembled monolayers modified gold electrode[J].Application Chemistry(应用化学),2005,22:172-175. [13]Raj C R,Okajima T,Ohsaka T.Gold nanoparticle ar-rys for the voltammetric sensing of dopamine[J].Elec-troanalytical Chemistry,2003,543:127-133. [14]Zhang H(张宏),Gui X Q(桂学琴),Jin B K(金葆康).Nanogold-modified glassy carbon electrode for selective detection of dopamine in the presence of as-corbic acid[J].Journal of Analytical Science(分析科学学报),2002,18:194-198.

[1]	Tesfaye Hailemariam Barkae, Mohamed Ibrahim Halawa, Tadesse Haile Fereja, Shimeles Addisu Kitte, 马显贵, 陈业权, 徐国宝. 鲁米诺/氨基磺酸电化学发光及其多巴胺检测应用[J]. 电化学（中英文）, 2021, 27(2): 168-176.
[2]	邢逸飞, 李娜, 温晓芳, 韩宏彦, 崔敏, 张聪, 任聚杰, 籍雪平. 基于取代型多酸复合材料的多巴胺电化学检测[J]. 电化学（中英文）, 2020, 26(6): 890-899.
[3]	张钰宁, 钮东方, 胡硕真, 张新胜. 基于纳米金属的增强效应在CO₂电还原反应中的应用进展[J]. 电化学（中英文）, 2020, 26(4): 495-509.
[4]	王来玉, 奚馨, 吴东清, 刘雄宇, 纪伟, 刘瑞丽. 有序介孔碳/石墨烯/镍泡沫的制备及其对多巴胺的高灵敏度和高选择性检测[J]. 电化学（中英文）, 2020, 26(3): 347-358.
[5]	张悦, 冯涛涛, 纪文亮, 张美宁. L-半胱氨酸和胱胺共自组装膜活体检测抗坏血酸[J]. 电化学（中英文）, 2019, 25(3): 400-408.
[6]	关利浩, 王超, 张望, 蔡雨露, 李凯, 林雨青. 快捷两步法制备金纳米电极用于活体多巴胺检测[J]. 电化学（中英文）, 2019, 25(2): 244-251.
[7]	张雅琳，陈驰，邹亮亮，邹志青，杨辉. Fe-N共掺杂的碳纳米管串联空心球对氧还原反应的电催化[J]. 电化学（中英文）, 2018, 24(6): 726-732.
[8]	陈禾木，邱晨曦，丛媛媛，刘会园，翟梓会，宋玉江. 酸处理的碳作为阳极电催化剂用于直接抗坏血酸碱性膜燃料电池[J]. 电化学（中英文）, 2018, 24(6): 748-756.
[9]	董鹏飞，李娜，赵海燕，崔敏，张聪，任聚杰，藉雪平. Keggin 型磷钨酸盐修饰碳糊电极传感多巴胺的研究[J]. 电化学（中英文）, 2018, 24(5): 555-562.
[10]	彭花萍, 余美玲, 刘馨, 刘盼, 陈伟, 刘爱林, 林新华*. 金纳米粒子/聚多巴胺/碳纳米管修饰玻碳电极对核黄素的测定[J]. 电化学（中英文）, 2016, 22(1): 43-48.
[11]	何芳，覃晓丽，傅迎春，陈超，谢青季*，姚守拙. 酶法合成的葡萄糖氧化酶-纳米金复合物的直接电化学与生物传感[J]. 电化学（中英文）, 2014, 20(6): 515-520.
[12]	黄春芳，姚桂红，邱建丁*. 表面分子印迹磁性纳米粒子的制备及其血红蛋白传感应用[J]. 电化学（中英文）, 2014, 20(6): 521-526.
[13]	王丽满, 林丽清, 翁少煌, 林新华, 陈元仲. 纳米金放大计时库仑法的PML/RARα融合基因检测[J]. 电化学（中英文）, 2012, 18(3): 286-290.
[14]	蔺首睿, 王立旭, 姜秀娥, 郭黎平. 纳米金三明治结构调制细胞色素c电子传递特性的分子机理研究[J]. 电化学（中英文）, 2012, 18(3): 263-268.
[15]	张英, 任旺, 李敏娇. 柠檬酸修饰(CA/GC)电极对抗坏血酸(AA)、多巴胺(DA)和尿酸(UA)的同时检测[J]. 电化学（中英文）, 2012, 18(1): 79-83.

纳米金双巯基修饰金电极差分脉冲伏安法测定多巴胺和抗坏血酸

Determination of Ddopamine and Ascorbate on Gold Nanoparticle and 4,4-bis (methanethiol) biphenyl (MTP) Self-assembled Monolayer Modified Gold Electrode

PDF (PC)

可视化

被引次数

摘要/Abstract

引用本文

使用本文

参考文献

相关文章 15

Metrics