基于取代型多酸复合材料的多巴胺电化学检测

doi:10.13208/j.electrochem.190716

电化学（中英文） ›› 2020, Vol. 26 ›› Issue (6): 890-899. doi: 10.13208/j.electrochem.190716

基于取代型多酸复合材料的多巴胺电化学检测

邢逸飞¹, 李娜¹, 温晓芳¹, 韩宏彦², 崔敏¹, 张聪¹, 任聚杰¹^,^*(), 籍雪平³^,^*()

^1. 河北科技大学理学院化学系,河北石家庄 050018
^2. 河北工业职业技术学院,河北石家庄 050091
^3. 河北医科大学药学院,河北石家庄 050017

收稿日期:2019-07-16 修回日期:2019-12-13 出版日期:2020-12-28 发布日期:2019-12-16
通讯作者: 任聚杰,籍雪平 E-mail:jujeren@163.com;xuepingji@126.com
基金资助:
河北科技大学博士启动基金No(81/1181222);大学生创新创业训练计划项目No(2018065);河北省高等学校科学技术研究项目No(ZD2018037);河北省高等学校科学技术研究项目No(QN2019032);与国家自然科学基金资助No(81872669)

Electrochemical Determination of Dopamine Based on Metal-Substituted Polyoxometalates Composites

XING Yi-fei¹, LI Na¹, WEN Xiao-fang¹, HAN Hong-yan², CUI Min¹, ZHANG Cong¹, REN Ju-jie¹^,^*(), JI Xue-ping³^,^*()

^1. Department of Chemistry, School of Science , Hebei University of Science and Technology, Shijiazhuang 050018, Hebei, China
^2. Department of Construction Engineering, Hebei College of Industry and Technology, Shijiazhuang 050091, Hebei, China
^3. School of Pharmacy,Hebei Medical University, Shijiazhuang 050017, Hebei, China

Received:2019-07-16 Revised:2019-12-13 Published:2020-12-28 Online:2019-12-16
Contact: REN Ju-jie,JI Xue-ping E-mail:jujeren@163.com;xuepingji@126.com

摘要/Abstract

摘要：

本文构建了基于取代型多酸与还原氧化石墨烯（RGO）复合材料的多巴胺电化学传感器. 首先,通过水热法合成了十一钨镍杂多钨硅酸盐K₂H₂SiW₁₁NiO₃₉·xH₂O（SiW₁₁Ni）,利用Hummers法与化学还原法合成了还原氧化石墨烯. 并使用SEM、XRD与FTIR等测试方法对材料进行了表征. 将SiW₁₁Ni与RGO按照一定的比例滴涂在玻碳电极表面,以便成功构建出传感界面（SiW₁₁Ni-RGO/GCE）. 然后,采用电化学阻抗法与循环伏安法等方法研究了传感界面的电化学性质. 优化实验条件后,利用该传感器通过循环伏安法对多巴胺进行定量检测,并且氧化过程展现出较为良好的性能. 其检出限为3.2 μmol·L ^-1（S/N = 3）,灵敏度为9.71 μA·(μmol·L ^-1·cm ^-2) ^-1,线性范围为10 ~ 80 μmol·L ^-1. 同时,所制备的传感器表现出良好的稳定性与抗干扰能力. 该传感器修饰过程简单、成本低、电化学性能良好,为多酸在化学传感领域的应用提供新思路.

关键词: 多巴胺, 电化学传感器, 多金属氧酸盐, 还原氧化石墨烯, 循环伏安法

Abstract:

In this report, a dopamine electrochemical sensor based on metal-substituted polyoxometalates and reduced graphene oxide (RGO) composite was successfully constructed. The K₂H₂SiW₁₁NiO₃₉·xH₂O (SiW₁₁Ni) was synthesized by hydrothermal method, while the RGO was prepared by Hummers' method and chemical reduction method. The above-mentioned materials were characterized by SEM, FTIR and XRD. The as-synthesized SiW₁₁Ni and RGO composites were modified on the surface of glassy carbon electrode (GCE) by drop coating method, and the sensing interface (SiW₁₁Ni-RGO/GCE) was successfully constructed. The electrochemical properties of the sensing interface were studied by electrochemical impedance spectroscopy and cyclic voltammetry. After optimizing the experimental conditions, dopamine could be quantitatively detected by cyclic voltammetry with good performance. The limit of detection was 3.2 μmol·L ^-1 (S/N = 3), the sensitivity was 9.71 μA·(μmol·L ^-1·cm ^-2) ^-1, and the linear range was 10 to 80 μmol·L ^-1.

Key words: dopamine, electrochemical sensor, polyoxometalates, reduced graphene oxide, cyclic voltammetry

中图分类号:

O657
O646

邢逸飞, 李娜, 温晓芳, 韩宏彦, 崔敏, 张聪, 任聚杰, 籍雪平. 基于取代型多酸复合材料的多巴胺电化学检测[J]. 电化学（中英文）, 2020, 26(6): 890-899.

XING Yi-fei, LI Na, WEN Xiao-fang, HAN Hong-yan, CUI Min, ZHANG Cong, REN Ju-jie, JI Xue-ping. Electrochemical Determination of Dopamine Based on Metal-Substituted Polyoxometalates Composites[J]. Journal of Electrochemistry, 2020, 26(6): 890-899.

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链接本文: https://electrochem.xmu.edu.cn/CN/10.13208/j.electrochem.190716

https://electrochem.xmu.edu.cn/CN/Y2020/V26/I6/890

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参考文献 38

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Electrode	Detection range/(μmol·L^-1)	LOD/(μmol·L^-1)	Sensitivity	Ref.
ERGO/GCE	0.5~60	0.5	0.482 μA·(μmol·L^-1)^-1	[33]
pHQ/AuNPs/NF	0.1~10	0.0419	6.663 μA·(μmol·L^-1)^-1	[34]
rGO-Co₃O₄/GCE	1~30	0.277	0.389 μA·(μmol·L^-1·cm^-2)^-1	[35]
BDD-NEAs	0.1~20	0.1	0.0597 μA·(μmol·L^-1·cm^-2)^-1	[36]
GO/GCE	1~15	0.27	0.5545 μA·(μmol·L^-1)^-1	[37]
Co[PW₁₂O₃₈]·5H₂O/CPE	8~30	5.4	0.039 μA·(μmol·L^-1)^-1	[38]
SiW₁₁Ni-RGO/GCE	10~80	3.2	0.686 μA·(μmol·L^-1)^-1	This work
SiW₁₁Ni-RGO/GCE	10~80	3.2	9.71 μA·(μmol·L^-1·cm^-2)^-1	This work

基于取代型多酸复合材料的多巴胺电化学检测

Electrochemical Determination of Dopamine Based on Metal-Substituted Polyoxometalates Composites

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