氧化铅掺杂碳纳米管糊预氧化电流型葡萄糖生物传感器的研究

电化学（中英文） ›› 2006, Vol. 12 ›› Issue (3): 319-323.

氧化铅掺杂碳纳米管糊预氧化电流型葡萄糖生物传感器的研究

漆红兰;张成孝;

陕西师范大学化学与材料科学学院,陕西师范大学化学与材料科学学院陕西西安710062,陕西西安710062

收稿日期:2006-08-28 修回日期:2006-08-28 出版日期:2006-08-28 发布日期:2006-08-28

Pre-oxidative Amperometric Glucose Biosensor Incorporated with Carbon Nanotube and PbO_(2)

QI Hong-lan,ZHANG Cheng-xiao~*

(School of Chemistry and Materials Science,Shaanxi Normal University,Xi'an 710062,Shaanxi,China

Received:2006-08-28 Revised:2006-08-28 Published:2006-08-28 Online:2006-08-28

摘要/Abstract

摘要： 以掺杂预氧化物质(二氧化铅)、电子介体(二茂铁羧酸)和碳纳米管作电极材料,研制预氧化电流型葡萄糖生物传感器.碳纳米管糊中掺入二氧化铅可消除抗坏血酸、尿酸等还原性物质对葡萄糖测定的干扰,该传感器在+0.40 V(vs.SCE)的工作电位下仍保持良好的抗干扰能力(对含有1.0 mmo.lL-1的葡萄糖溶液,1.8 mmo.lL-1的抗坏血酸和2.2 mmo.lL-1的尿酸均不产生干扰)和较快的响应速率(10 s),响应电流与葡萄糖浓度在0.50~20 mmo.lL-1范围内呈良好的线性关系,相关系数为0.9987.此传感器用于人体血清中葡萄糖的测定,结果满意.

关键词: 生物传感器, 预氧化, 二氧化铅, 碳纳米管

Abstract: A pre-oxidative amperometric glucose biosensor incorporated with carbon nanotube,ferrocenemonocarboxylic acid and PbO_(2) was designed.The interferences coming from reduced substances,such as ascoribic acid and urine acid were eliminated by PbO_(2).The oxidative current is linear at the potential of +0.40 V(vs.SCE) to the concentration of glucose in the range from 0.50 to 20 mmol·L~(-1),and the detection limit of glucose is 0.1 mol L~(-1).The relative standard deviation is 3.3% for seven successive assays at 5.0 mmol·L~(-1)glucose.This biosensors have been applied to determination of the glucose in serum with satisfying results.

Key words: Biosensor, Pre-oxidation, PbO_(2), Carbon nanotube, Glucose

中图分类号:

TP212.3

漆红兰;张成孝;. 氧化铅掺杂碳纳米管糊预氧化电流型葡萄糖生物传感器的研究[J]. 电化学（中英文）, 2006, 12(3): 319-323.

QI Hong-lan,ZHANG Cheng-xiao~*. Pre-oxidative Amperometric Glucose Biosensor Incorporated with Carbon Nanotube and PbO_(2)[J]. Journal of Electrochemistry, 2006, 12(3): 319-323.

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https://electrochem.xmu.edu.cn/CN/Y2006/V12/I3/319

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