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电化学(中英文) ›› 2007, Vol. 13 ›› Issue (2): 216-219.  doi: 10.61558/2993-074X.1811

• 研究论文 • 上一篇    下一篇

金电极上放线菌素D的电化学行为及分析测定

朱清涛;廖钫;何晓英;   

  1. 西华师范大学化学化工学院,西华师范大学化学化工学院,西华师范大学化学化工学院 四川南充637002,四川南充637002,四川南充637002
  • 收稿日期:2007-05-28 修回日期:2007-05-28 出版日期:2007-05-28 发布日期:2007-05-28

Square Wave Stripping Voltammetric Behaviors of Actinomycin D on Glod Electrode and Its Application

ZHU Qing-tao,LIAO Fang,HE Xiao-ying   

  1. (Institute of Chemical Engineering,China West Normal University,Nanchong 637002,Sichuan,China
  • Received:2007-05-28 Revised:2007-05-28 Published:2007-05-28 Online:2007-05-28

摘要: 应用方波溶出伏安法研究了放线菌素D在KH2PO4-Na2HPO4缓冲溶液中于金电极上的电化学行为以及酸度、预富集沉积电位、预富集沉积时间、方波频率、方波幅度、电位增量等的影响,优化测定参数,建立一种直接测定放线菌素D的电分析测定方法.在0.1~10.0μmol.L-1浓度范围内,放线菌素D与其方波溶出伏安氧化峰电流呈良好的线性关系,相关系数0.9991,检测限1.0×10-8mol.L-1.

关键词: 放线菌素D, 方波溶出伏安法, 金电极, 电化学检测

Abstract: The electrochemical behaviors of Actinomycin D(ACTD)at glod electrode were investigated by square wave stripping voltammeter in the KH2PO4-Na2HPO4 buffer solution(pH=5.90).The sensitive oxidation peak of ACTD was observed and the potential peak for ACTD is-0.17 V(vs.SCE).The Experimental parameters,such as pH value,amplitude,accumulation potential and time were optimized,and a direct electroanalytical method for determining ACTD was developed.The peak currents were proportional to the concentration of ACTD in the range of 0.1μmol·L-1~10.0μmol·L-1,and the linear regression coefficient equaled 0.9991.The detection limit for ACTD was 1.0×10-8mol·L-1.

Key words: Actinomycin D, square wave stripping voltammeter, glod electrode, electroanalytical chemistry

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