对乙酰氨基酚在活化玻碳电极上的电化学行为及测定

doi:10.61558/2993-074X.1939

电化学（中英文） ›› 2008, Vol. 14 ›› Issue (4): 441-445. doi: 10.61558/2993-074X.1939

对乙酰氨基酚在活化玻碳电极上的电化学行为及测定

谭宝玉;廖钫;何晓英;朱清涛;华俊;蒋晓丽;

西华师范大学化学化工学院;

收稿日期:2008-11-28 修回日期:2008-11-28 出版日期:2008-11-28 发布日期:2008-11-28

Electrochemical Behavior and Determination of Paracetamol on Activated Glassy Carbon Electrode

TAN Bao-yu,LIAO Fang,HE Xiao-Ying*,ZHU Qing-tao,HUA Jun,JIANG Xiao-li

(Institute of Chemical Engineering,China West Normal University,Nanchong 637002,Sichuan,China

Received:2008-11-28 Revised:2008-11-28 Published:2008-11-28 Online:2008-11-28

摘要/Abstract

摘要： 应用循环伏安法,研究了对乙酰氨基酚(PCT)在活化玻碳电极上的电化学行为.在pH=4.00的HAc-NaAc缓冲溶液中,PCT的CV扫描于0.54 V左右出现一对明显的氧化-还原峰.电极反应为2电子、2质子的受吸附控制的准可逆过程.其氧化峰电流与PCT浓度在8.00×10-6~2.00×10-4mol.L-1范围内呈良好的线性关系,相关系数r=-0.99918;检出限为6.34×10-6mol.L-1.用于药物样品PCT的含量测定,结果满意.

关键词: 对乙酰氨基酚, 活化, 玻碳电极, 循环伏安

Abstract: The electrochemical behavior of paracetamol(PCT) was studied at glassy carbon electrode activated by cyclic voltammetry.In HAc-NaAc buffer solution(pH=4.00),a couple of sensitive redox peaks were recorded about 0.54 V in the cyclic voltammograms.The result indicated that the process was controlled by adsorption and nearly reversible.The reaction electron and proton numbers were estimated,respectively,to be two.Excllent linearity was observed in the correlation between the oxidation peak current and the concentration of PCT in the range of 8.00×10-6～2.00×10-4 mol·L-1.The correlative coefficient was-0.999 18.The detection limit was 6.34×10-6 mol·L-1.This method can be used for the determination of PCT real samples.

Key words: paracetamol, activation, glassy carbon electrode, cyclic voltammetry

中图分类号:

R927

谭宝玉, 廖钫, 何晓英, 朱清涛, 华俊, 蒋晓丽, . 对乙酰氨基酚在活化玻碳电极上的电化学行为及测定[J]. 电化学（中英文）, 2008, 14(4): 441-445.

TAN Bao-yu, LIAO Fang, HE Xiao-Ying, ZHU Qing-tao, HUA Jun, JIANG Xiao-li. Electrochemical Behavior and Determination of Paracetamol on Activated Glassy Carbon Electrode[J]. Journal of Electrochemistry, 2008, 14(4): 441-445.

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https://electrochem.xmu.edu.cn/CN/Y2008/V14/I4/441

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对乙酰氨基酚在活化玻碳电极上的电化学行为及测定

Electrochemical Behavior and Determination of Paracetamol on Activated Glassy Carbon Electrode

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