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电化学(中英文) ›› 2007, Vol. 13 ›› Issue (3): 238-241. 

• 研究论文 • 上一篇    下一篇

电化学共沉积HA/胶原复合涂层及其生物性能初探

徐艳丽;林龙翔;耿志旺;林昌健;   

  1. 厦门大学化学化工学院固体表面物理化学国家重点实验室,厦门大学化学化工学院固体表面物理化学国家重点实验室,厦门大学化学化工学院固体表面物理化学国家重点实验室,厦门大学化学化工学院固体表面物理化学国家重点实验室 福建厦门361005,福建厦门361005,福建厦门361005,福建厦门361005
  • 收稿日期:2007-08-28 修回日期:2007-08-28 出版日期:2007-08-28 发布日期:2007-08-28

Electrochemical Codeposition of HA/Collagen Coating and Preliminary in Vitro Tests

XU Yan-li,LIN Long-xiang,GENG Zhi-wang,LIN Chang-jian*   

  1. (State Key Laboratary of Physical Chemistry of Solid Surfaces,Department of Chemistry,Xiamen University,Xiamen 361005,Fujian,China
  • Received:2007-08-28 Revised:2007-08-28 Published:2007-08-28 Online:2007-08-28

摘要: 应用电化学恒电流共沉积法在医用纯钛基底上制备羟基磷灰石(HA)/胶原(collagen)复合涂层.SEM和XPS等测试表明:复合涂层呈特定有序的纳-微米二级多孔结构,化学组分为HA和胶原的有机-无机复合.借助体外细胞的培养实验观察种植于不同材料表面的细胞贴壁及生长形态,显示电化学共沉积的复合涂层具有比纯HA或纯钛表面更好的生物相容性.

关键词: 羟基磷灰石, Ⅰ型胶原, 复合涂层, 电化学共沉积, 生物性能

Abstract: An electrochemical co-deposition technique has been developed to prepare a hydroxyapatite(HA)/collagen composite coating on Ti substrate.The SEM results show that the composite coating exhibits a homogeneous and porous morphology with nano-micro structure.And the XPS results demonstrate that the composite coating is formed by an organic-inorganic hybrization.In vitro cell culture tests reveal that,compared with pure HA and pure Ti,the HA/collagen composite coating exhibit a best biological properties.

Key words: hydroxyapatite, Ⅰtype collagen, composite coatings, electrochemical co-deposition, bioproperty

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