电沉积铋膜电极差示脉冲溶出伏安法测定盐酸左氧氟沙星

doi:10.13208/j.electrochem.180924

电化学（中英文） ›› 2019, Vol. 25 ›› Issue (6): 792-801. doi: 10.13208/j.electrochem.180924

电沉积铋膜电极差示脉冲溶出伏安法测定盐酸左氧氟沙星

郭子英，李作鹏^*，李江，赵建国，冯锋^*

山西大同大学化学与环境工程学院，山西大同 037009

收稿日期:2018-09-26 修回日期:2018-12-04 出版日期:2019-12-28 发布日期:2019-12-28
通讯作者: 李作鹏;冯锋 E-mail:lizuopeng@126.com；feng-feng64@263.net
基金资助:
This work was financially supported by Natural Science Foundation of Daton(No. 2019168, No. 201819), Natural Science Foundation of Shanxi Province (No. 201701D121016) and research funds of Innovation & Application Engineering Research Center for Mesoporous Materials of Shanxi Province (No. MMIA2019105).

Quantitative Detection of Levofloxacin Hydrochloride by Differential Pulse Stripping Voltammetry with Electrodeposited Bismuth Film Electrodes

GUO Zi-ying, LI Zuo-peng^*, LI Jiang, ZHAO Jian-guo, FENG Feng^*

School of Chemistry and Enviromental Engineering, Shanxi Datong University, Datong, 037009, China

Received:2018-09-26 Revised:2018-12-04 Published:2019-12-28 Online:2019-12-28
Contact: Li Zuo-peng;Feng Feng E-mail:lizuopeng@126.com；feng-feng64@263.net

摘要/Abstract

摘要： 盐酸左氧氟沙星分子中含有弱酸性有机胺结构，可与Zn(SCN)₄^2-形成离子缔合物沉淀. 将沉淀分离溶解后，用差示脉冲溶出伏安法在原位形成铋膜电极上测定沉淀中锌(II)的含量，间接测定盐酸左氧氟沙星的含量，结果表明，采用铋膜电极伏安曲线峰形好、灵敏度高、峰电流值大，方法的线性回归方程为I = 1.1401c - 0.5309，相关系数R = 0.9979，线性范围为5.0 ~ 60 μg·mL^-1，检出限为3.18×10^-5 μg·mL^-1，回收率为95% ~ 101%，相对标准偏差RSD = 2.87%.

关键词: 铋膜电极, 差示脉冲溶出伏安法, 盐酸左氧氟沙星, 锌离子, 离子缔合物

Abstract: In this study, differential pulse stripping voltammetry was developed for the quantitative detection of levofloxacin hydrochloride indirectly. Levofloxacin hydrochloride contains organic amine, which can be precipitated upon interaction with Zn(SCN)₄^2-. By means of differential pulse stripping voltammetry, the concentration of Zn²⁺ can be determined using an in-situ formed bismuth film electrode, which allows determining indirectly the amount of levofloxacine hydrochloride. The linearity equation, I = 1.1401c - 0.5309 with the correlative coefficient R = 0.9979, was presented in the experiment. The results showed that this approach is very sensitive, having a limitation of detection of 3.18 × 10^-5 μg·mL^-1 in a linearity range of 5.0 ~ 60 μg·mL^-1.

Key words: bismuth film electrode, differential pulse stripping voltammetry, levofloxacine hydrochloride, zinc ion, ion-association compound

中图分类号:

O646

郭子英, 李作鹏, 李江, 赵建国, 冯锋. 电沉积铋膜电极差示脉冲溶出伏安法测定盐酸左氧氟沙星[J]. 电化学（中英文）, 2019, 25(6): 792-801.

GUO Zi-ying, LI Zuo-peng, LI Jiang, ZHAO Jian-guo, FENG Feng. Quantitative Detection of Levofloxacin Hydrochloride by Differential Pulse Stripping Voltammetry with Electrodeposited Bismuth Film Electrodes[J]. Journal of Electrochemistry, 2019, 25(6): 792-801.

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https://electrochem.xmu.edu.cn/CN/Y2019/V25/I6/792

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电沉积铋膜电极差示脉冲溶出伏安法测定盐酸左氧氟沙星

Quantitative Detection of Levofloxacin Hydrochloride by Differential Pulse Stripping Voltammetry with Electrodeposited Bismuth Film Electrodes

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