研究了阿霉素（ADM）在β-环糊精（β-CD）修饰金电极上的电化学行为，结果表明，β-CD/Au电极ADM发生表面包络反应。25 ℃，pH=7.0时，该电极表面包络常数为9.54×104 L?mol-1，表面包络常数随温度呈规律性变化，最适宜反应温度为30℃。该电极ADM包络呈准可逆的电化学反应，其速率常数为0.0995 s-1。在20~40 μmol?L-1浓度范围β-CD/Au电极ADM的还原峰电流与浓度呈线性关系，线性方程 Ip=2.024+0.0057C，相关系数0.9911，检出限6.5 μmol?L-1。

The β-cyclodextrin (β-CD) modified gold electrode (β-CD/Au) was fabricated to study the electrochemical behavior of adriamycin (ADM). The results indicated that the complexing reaction of ADM with β-CD took place at the β-CD/Au surface. At 25 ℃，the complexing constant (K) was 9.54×104 L?mol-1 in pH=7.0. The K values changed regularly with temperature, and the most suitable temperature of the surface inclusion reaction was 30 ℃. The complexing reaction of ADM with β-CD at the β-CD/Au surface could undergo the quasi-reversible electrochemical reaction with the rate constant being 0.0995 s-1. The cathodic peak current (Ip) of ADM was proportional to the concentration of ADM in the 20~40 μmol?L-1. The linear regression equation for the quantitative determination of ADM concentration (C) by β-CD/Au was Ip=2.024+0.0057C with a correlation coefficient of 0.9911. The detection limit was 6.5 μmol?L-1.