双极电极-电致化学发光技术在生物分析中的应用

doi:10.13208/j.electrochem.140444

电化学（中英文） ›› 2015, Vol. 21 ›› Issue (1): 1-7. doi: 10.13208/j.electrochem.140444

• 生物电分析化学近期研究专辑（南京大学夏兴华教授主编） • 下一篇

双极电极-电致化学发光技术在生物分析中的应用

吴梅笙^1,2，徐静娟^1*，陈洪渊¹

1. 南京大学生命分析化学国家重点实验室，化学化工学院，江苏南京 210093；2. 南京农业大学理学院化学系，江苏南京 210098

收稿日期:2014-11-12 修回日期:2014-12-01 出版日期:2015-02-28 发布日期:2014-12-07
通讯作者: 徐静娟 E-mail:xujj@nju.edu.cn
基金资助:
国家自然科学基金项目（No. 21025522, No. 21121091, No. 21305068）资助

Electrochemiluminescence Assay Based on Bipolar Electrode for Bioanalysis

WU Mei-sheng^1,2, XU Jing-juan^1*, CHEN Hong-yuan¹

1. State Key Laboratory of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093, China; 2. Department of Chemistry, College of Science, Nanjing Agricultural University, Nanjing 210095, China

Received:2014-11-12 Revised:2014-12-01 Published:2015-02-28 Online:2014-12-07
Contact: XU Jing-juan E-mail:xujj@nju.edu.cn

摘要/Abstract

摘要： 在微管道两端施加一定的电压时，置于这个电场中的金属或半导体带与溶液的界面电势差达到一定的数值后，就会引起溶液电活性物质在其两端发生氧化还原反应，该金属或半导体带即称为双极电极（BPE）. BPE与电致化学发光（ECL）技术的完美结合有诸多优点，如浓度富集、灵敏度高、成本低、装置轻便且不需要外加光源等，极适合生物分析检测. 本文综述了双极电极-电致化学发光技术在生物分析中的应用，并展望相关发展趋势.

关键词: 双极电极, 电致化学发光, 钌联吡啶, 阵列传感器

Abstract: Bipolar electrodes (BPEs) are electronic conductors which are usually embedded into microchannels. The potential difference at the BPE/solution interface is obtained by applying a voltage at the two ends of the microchannel. When it reaches a critical value, the redox reaction takes place at both poles of the BPE simultaneously. Compared with other detection methods, the electrochemiluminescence (ECL) platform based on BPE possesses the advantages of concentration enrichment, high sensitivity, low cost, portable sensor system, no need for a light source, which is quite suitable for bioanalysis. This paper reviews the ECL-BPE strategy for bioanalysis and proposes the future research trends.

Key words: bipolar electrode, electrochemiluminescence, Ru(bpy)₃²⁺, biosensor array

中图分类号:

O646

吴梅笙，徐静娟*，陈洪渊. 双极电极-电致化学发光技术在生物分析中的应用[J]. 电化学（中英文）, 2015, 21(1): 1-7.

WU Mei-sheng, XU Jing-juan*, CHEN Hong-yuan. Electrochemiluminescence Assay Based on Bipolar Electrode for Bioanalysis[J]. Journal of Electrochemistry, 2015, 21(1): 1-7.

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链接本文: https://electrochem.xmu.edu.cn/CN/10.13208/j.electrochem.140444

https://electrochem.xmu.edu.cn/CN/Y2015/V21/I1/1

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双极电极-电致化学发光技术在生物分析中的应用

Electrochemiluminescence Assay Based on Bipolar Electrode for Bioanalysis

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