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研究论文

木犀草素在玻碳电极上的直接电化学行为及其测定

  • 刘爱林 ,
  • 张少波 ,
  • 吴潇霎 ,
  • 李丽萍 ,
  • 曹扬远 ,
  • 黄丽英 ,
  • 林新华
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  • 福建医科大学药学院药物分析系,福建医科大学药学院药物分析系,福建医科大学药学院药物分析系,福建医科大学药学院药物分析系,福建医科大学药学院药物分析系,福建医科大学药学院药物分析系,福建医科大学药学院药物分析系 福建福州350004,福建福州350004,福建福州350004,福建福州350004,福建福州350004,福建福州350004,福建福州350004

收稿日期: 2007-11-28

  修回日期: 2007-11-28

  网络出版日期: 2007-11-28

Electrochemical Behavior and Determination of Luteolin at a Glassy Carbon Electrode

  • LIU Ai-lin ,
  • ZHANG Shao-bo ,
  • WU Xiao-sha ,
  • LI Li-ping ,
  • CAO Yang-yuan ,
  • HUANG Li-ying ,
  • LIN Xin-hua
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  • (Department of Pharmaceutical Analysis of the Fujian Meidical University,Fuzhou 350004,China

Received date: 2007-11-28

  Revised date: 2007-11-28

  Online published: 2007-11-28

摘要

应用循环伏安法研究木犀草素于玻碳电极的电化学行为.在磷酸盐缓冲液中(pH 4.0),-0.2~+0.8V电位区间内,木犀草素于玻碳电极表面发生的电极反应是吸附控制的准可逆2电子转移过程,电子转移系数α=0.66;建立了检测木犀草素含量的差示脉冲伏安法(DPV).在富集电位+0.4 V下,经富集240 s后,测得木犀草素氧化峰电流Ip与其浓度在1.0×10-8~1.0×10-6mol.L-1范围内呈良好的线性关系,最低检出限为5.0×10-9mol.L-1.本法操作简单、快速、灵敏、准确,可为木犀草素药物质量的控制和检测提供一种简便的新方法.

本文引用格式

刘爱林 , 张少波 , 吴潇霎 , 李丽萍 , 曹扬远 , 黄丽英 , 林新华 . 木犀草素在玻碳电极上的直接电化学行为及其测定[J]. 电化学, 2007 , 13(4) : 441 -444 . DOI: 10.61558/2993-074X.1850

Abstract

The electrochemical behavior of luteolin was studied by voltammetry at a glassy carbon electrode in phosphate buffer solution.The results exhibited that the well-defined redox peak of luteolin is observed and the electrode process is adsorption-controlled.The charge transfer coefficient(α) was calculated as 0.66 in phosphate buffer solution(pH 4.0).The relationships between oxidation peak current and the concentration of luteolin are linear in the range of 1.0×10-8 ~ 5.0×10-6 mol·L-1 by differential pulse voltammetric method.The detection limit had been estimated as 1.0×10-8 molL-1.This method can be used for the determination of luteolin with satisfactory results.

参考文献

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