单颗粒碰撞电化学近年来已得到迅速发展并在纳米颗粒的性质分析及包括DNA、RNA、蛋白质、酶、细菌、病毒、囊泡类物质等生物体的检测上展示出广阔的前景. 在这篇综述中，作者总结了近年来单颗粒碰撞电化学在电化学分析中的进展，按分析检测的策略不同分为以下几个部分阐述：纳米粒子或标记纳米粒子的直接电解；包含氧化还原活性分子的软颗粒的直接电解；颗粒的间接电化学行为；区域扩散阻塞效应；电流强度及碰撞频率的改变.

Single particle impact electrochemistry (SPIEC) has grown rapidly in recent years and shown great promise in the analysis of nanoparticle properties as well as the detection of biomolecules including DNA, RNA, protein, enzyme, bacteria, virus, vesicles and others. This minireview summarizes recent advances in electroanalytical applications of SPIEC according to different analytical methods, i.e., direct electrolysis of nanoparticles or labeled nanoparticles, direct electrolysis of soft particles encapsulated redox molecule, indirect electrochemistry of particles, area and diffusion blocking, and changes in current magnitude and collision frequency.