基于BCNTs/GC电极的鸟嘌呤与腺嘌呤电化学行为及其同时检测

doi:10.61558/2993-074X.2932

电化学（中英文） ›› 2012, Vol. 18 ›› Issue (4): 365-370. doi: 10.61558/2993-074X.2932

基于BCNTs/GC电极的鸟嘌呤与腺嘌呤电化学行为及其同时检测

夏雅淋², 邓春艳^1*, 向娟¹

1. 中南大学有色金属资源化学教育部重点实验室，化学化工学院，湖南长沙410083；2. 湖南大学化学生物传感与计量学国家重点实验室，化学化工学院，湖南长沙410082

收稿日期:2012-03-15 修回日期:2012-04-15 出版日期:2012-08-28 发布日期:2012-04-20
通讯作者: 邓春艳 E-mail:dengchunyan@csu.edu.cn
基金资助:
国家自然科学基金项目（No. 21005090）和湖南大学化学生物传感与计量学国家重点实验室开放基金资助

Electrochemical Sensing of Guanine and Adenine Based on the Boron-doped Carbon Nanotubes Modified Electrode

XIA Ya-Lin², DENG Chun-Yan^1*, XIANG Juan¹

1. Key Laboratory of Resources Chemistry of Nonferrous Metals, Central South University, Changsha 410083, China; 2. State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha 410082, China

Received:2012-03-15 Revised:2012-04-15 Published:2012-08-28 Online:2012-04-20
Contact: DENG Chun-yan E-mail:dengchunyan@csu.edu.cn

摘要/Abstract

摘要： 利用掺硼碳纳米管（BCNTs）/GC电极研究了鸟嘌呤（G）和腺嘌呤（A）的电化学氧化行为. 与GC和CNTs/GC电极相比，BCNTs/GC电极具有更强的电催化活性，且响应电流明显增加. 两混合样品在BCNTs/GC电极上的氧化峰间隔较大，可实现对A和G的同时检测.

关键词: 掺硼碳纳米管, 鸟嘌呤, 腺嘌呤

Abstract: In this work, the boron-doped carbon nanotubes (BCNTs) modified glassy carbon (GC) electrode was simply fabricated, and the electrochemical oxidation behaviors of guanine and adenine at the BCNTs/GC electrode were investigated. Compared with the bare GC and CNTs/GC electrodes, the BCNTs-modified electrode exhibited extraordinary electrocatalytic activity towards the oxidations of guanine and adenine as indicated by the obvious increase in current responses. Moreover, the peak separation between guanine and adenine was large enough for their potential recognition in mixture without any separation or pretreatment. Therefore, the simultaneous determination of guanine and adenine was successfully achieved. The BCNTs/GC electrode showed high sensitivity, wide linear range and low detection limit for the electrochemical determination of guanine and adenine. The possibility of the BCNTs/GC electrode for the determination of guanine and adenine in calf thymus DNA has also been evaluated. The BCNTs/GC electrode has advantages of excellent catalytic activity, selectivity and simplicity, which play a potential role in the development of the related DNA analysis.

Key words: boron-doped carbon nanotubes, guanine, adenine

中图分类号:

O646

夏雅淋, 邓春艳, 向娟. 基于BCNTs/GC电极的鸟嘌呤与腺嘌呤电化学行为及其同时检测[J]. 电化学（中英文）, 2012, 18(4): 365-370.

XIA Ya-Lin, DENG Chun-Yan, XIANG Juan. Electrochemical Sensing of Guanine and Adenine Based on the Boron-doped Carbon Nanotubes Modified Electrode[J]. Journal of Electrochemistry, 2012, 18(4): 365-370.

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https://electrochem.xmu.edu.cn/CN/Y2012/V18/I4/365

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基于BCNTs/GC电极的鸟嘌呤与腺嘌呤电化学行为及其同时检测

Electrochemical Sensing of Guanine and Adenine Based on the Boron-doped Carbon Nanotubes Modified Electrode

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