关键词: 示波分析, 示波测定, 药物分析, 酚磺乙胺

Abstract: In 0.2 mol L~(-1) NaOH solution, ethamsylate can yield a sensitive incision on cathodic branch of dE/dt-E osillogram at 0.3V (vs. SCE). Based on the oscillographic characteristic, a second order differential simple oscillographic voltammetry for determination of ethamsylate in tablet and injection is presented in this paper. The peak height on second order differential simple oscillographic voltammogram is linearly proportional to concentration of the ethamsylate in the range of 1.5×10~(-5)～3.4×10~(-4) mol·L~(-1 )with a 0.9921 correlation coefficient and a detection limit of 6.0×10~(-6 )mol·L~(-1 ) for ethamsylate. The relative standard deviation is 2.1% for the determination of 3.0 10~(-5) mol L~(-1) ethamsylate (n=5). Compared with HPLC and other methods, the second order differential simple oscillographic voltammetry is a convenient method due to its cheap equipment and rapid measurement.