金属有机框架功能化的纳米通道对锶离子进行高灵敏度检测

王旭刚, 何正旭, 丁德芳, 罗雪芹, 戴力, 张炜奇, 马群, 黄羽, 夏帆

Highly Sensitive Detection of Strontium Ions Using Metal-Organic Frameworks Functionalized Solid-State Nanochannels

Xu-Gang Wang, Zheng-Xu He, De-Fang Ding, Xue-Qin Luo, Li Dai, Wei-Qi Zhang, Qun Ma, Yu Huang, Fan Xia

Fig. 5. Schematic diagrams showing the sensing mechanisms of APT/AAO and APT/MOF/AAO. (a) Process of aptamer-modified nanochannel recognition of Sr2+. Before the target is recognized, the aptamer is stretched to clog the nanochannels (Closed), after binding to the target, the aptamer is induced by Sr2+, and the aptamer folds into a G-quadruplex structure to open the nanochannel (Open). As a result, the nanopore diameter changes from d to d+∆d. (b, c) Side views of the APT/AAO and APT/MOF/AAO detection processes, respectively. The results indicate that the APT/MOF/AAO has higher sensitivity than the APT/AAO due to the synergistic effect of 2D nanosheets and specific probes.